The Pediatric Sedation Research Consortium (PSRC) has continued to be a source of data for researchers exploring novel questions about procedural sedation. James Hertzog et al. published, “Incidence and Nature of Allergic and Anaphylactic Reactions During Pediatric Procedural Sedation: A Report from the Pediatric Sedation Research Consortium,” in the January 2019 volume of Hospital Pediatrics. The authors were able to retrospectively evaluate 227,833 cases and determine that 54 cases of allergic reaction, six consistent with anaphylaxis, were reported. Utilizing data entered on each of these cases, they were then able to determine if there were associations between any of the medications and the reported event.
The preceding is a great example of utilizing a database comprised of multiple institutions with a variety of delivery models to help determine the causative factors behind these rare events. This type of research would not be possible without the collaboration and dedication of all of these institutions. Other projects underway and their current status are as follows:
- Anticholinergic Drugs and Adverse Events
– Poster to be presented - Trends in Drug Use
– Poster presented; manuscript in preparation - MRI sedation
– Poster presented; manuscript in preparation - Procedures proximal to airway
– Manuscript submitted - Desaturation Data (QA)
– Details of request being submitted - Intranasal DEX Study Study
– Data collection tool in development - Chloral Hydrate Project
– Awaiting proposal - Burn Injuries Sedation
– Awaiting final version of the proposal - IN Midazolam Project
– Should be approved to move forward - Developmental Delay Data
– Awaiting final version of the proposal
